Home
Career Stage
Medical Students Residents Attendings CPT Codes Resources Blog Support

A2004 Xcellistem, 1 milligrams

A Codes

Also known as: XCELLISTEM, collagen hyaluronic acid, hybrid matrix

XCELLISTEM, Acellular Collagen and Hyaluronic Acid Matrix 1 milligram, a biologic wound dressing combining collagen with hyaluronic acid for enhanced wound healing.

In Plain Language

hybrid wound graft; collagen-based wound dressing

Clinical Context

Used for diabetic ulcers, venous leg ulcers, traumatic wounds, and surgical sites where combined collagen and hyaluronic acid support is indicated.

RVU Information

CPT A2004 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

HCPCS A-codes cover medical supplies, equipment, and transport services. Documentation must establish medical necessity and include a physician order. For durable medical equipment (DME), a Certificate of Medical Necessity (CMN) or detailed written order may be required.

Specialties

Wound CareDermatologySurgery

Frequently Asked Questions

What is CPT code A2004?

CPT A2004 (Xcellistem, 1 milligrams) is a A Codes code. XCELLISTEM, Acellular Collagen and Hyaluronic Acid Matrix 1 milligram, a biologic wound dressing combining collagen with hyaluronic acid for enhanced wound healing.

Does Medicare cover A2004?

Medicare coverage for A2004 depends on medical necessity and applicable Local Coverage Determinations (LCDs). Used for diabetic ulcers, venous leg ulcers, traumatic wounds, and surgical sites where combined collagen and hyaluronic acid support is indicated. A physician order is typically required.

When is CPT A2004 used?

Used for diabetic ulcers, venous leg ulcers, traumatic wounds, and surgical sites where combined collagen and hyaluronic acid support is indicated.

Track This Code in RVU Edge

Log procedures, calculate wRVUs, and benchmark against national data — all in one app.

CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.