J0224 Injection. lumasiran, 0.5 milligrams
Also known as: lumasiran, Oxlumo
Lumasiran injection 0.5 milligram, a small interfering ribonucleic acid (siRNA) for primary hyperoxaluria type 1.
In Plain Language
kidney disease prevention therapy; genetic kidney disease treatment
Clinical Context
Intravenous siRNA that silences hepatic lactate dehydrogenase in primary hyperoxaluria type 1. Reduces oxalate production and urinary excretion, preventing kidney damage.
RVU Information
CPT J0224 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J0224?
CPT J0224 (Injection. lumasiran, 0.5 milligrams) is a J Codes (Drugs) code. Lumasiran injection 0.5 milligram, a small interfering ribonucleic acid (siRNA) for primary hyperoxaluria type 1.
How is J0224 administered?
CPT J0224 is administered by a healthcare provider, typically via injection or infusion. Intravenous siRNA that silences hepatic lactate dehydrogenase in primary hyperoxaluria type 1. Reduces oxalate production and urinary excretion, preventing kidney damage. It is used by Genetics, Nephrology, Internal Medicine.
When is CPT J0224 used?
Intravenous siRNA that silences hepatic lactate dehydrogenase in primary hyperoxaluria type 1. Reduces oxalate production and urinary excretion, preventing kidney damage.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.