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J0594 Busulfan injection

J Codes (Drugs)

Also known as: busulfan, Busulfex, alkylating agent

Busulfan injection for intravenous administration, an alkylating agent chemotherapy drug used in conditioning regimens for hematopoietic stem cell transplantation.

In Plain Language

bone marrow conditioning medication; cancer/transplant preparation drug

Clinical Context

Used as myeloablative conditioning agent prior to hematopoietic stem cell transplantation for chronic myeloid leukemia and other hematologic malignancies. Administered via central line with intensive supportive care.

RVU Information

CPT J0594 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

hematology/oncologybone marrow transplanthospital medicine

Frequently Asked Questions

What is CPT code J0594?

CPT J0594 (Busulfan injection) is a J Codes (Drugs) code. Busulfan injection for intravenous administration, an alkylating agent chemotherapy drug used in conditioning regimens for hematopoietic stem cell transplantation.

How is J0594 administered?

CPT J0594 is administered by a healthcare provider, typically via injection or infusion. Used as myeloablative conditioning agent prior to hematopoietic stem cell transplantation for chronic myeloid leukemia and other hematologic malignancies. Administered via central line with intensive supportive care. It is used by hematology/oncology, bone marrow transplant, hospital medicine.

When is CPT J0594 used?

Used as myeloablative conditioning agent prior to hematopoietic stem cell transplantation for chronic myeloid leukemia and other hematologic malignancies. Administered via central line with intensive supportive care.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.