J0597 C-1 esterase, berinert
Also known as: berinert, C1-INH plasma-derived, esterase inhibitor
C1 esterase inhibitor (Berinert) injection, plasma-derived product for acute treatment of hereditary angioedema attacks and prophylactic use.
In Plain Language
hereditary swelling blocker injection; angioedema emergency treatment
Clinical Context
Plasma-derived C1 esterase inhibitor concentrate for acute HAE attacks and short-term prophylaxis. Rapidly replaces deficient C1-INH to restore complement regulation and prevent further edema formation.
RVU Information
CPT J0597 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J0597?
CPT J0597 (C-1 esterase, berinert) is a J Codes (Drugs) code. C1 esterase inhibitor (Berinert) injection, plasma-derived product for acute treatment of hereditary angioedema attacks and prophylactic use.
How is J0597 administered?
CPT J0597 is administered by a healthcare provider, typically via injection or infusion. Plasma-derived C1 esterase inhibitor concentrate for acute HAE attacks and short-term prophylaxis. Rapidly replaces deficient C1-INH to restore complement regulation and prevent further edema formation. It is used by allergy, immunology, emergency medicine.
When is CPT J0597 used?
Plasma-derived C1 esterase inhibitor concentrate for acute HAE attacks and short-term prophylaxis. Rapidly replaces deficient C1-INH to restore complement regulation and prevent further edema formation.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.