J0666 Injection, bupivacaine liposome
Also known as: bupivacaine liposome, Exparel, liposomal formulation
Bupivacaine liposome injection, a proprietary formulation with enhanced tissue penetration for local and regional anesthesia with prolonged duration.
In Plain Language
extended-acting numbing injection; long-lasting pain relief anesthetic
Clinical Context
Liposomal encapsulation of bupivacaine providing extended anesthesia duration up to 72 hours, used in surgical infiltration, nerve blocks, and regional anesthesia.
RVU Information
CPT J0666 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J0666?
CPT J0666 (Injection, bupivacaine liposome) is a J Codes (Drugs) code. Bupivacaine liposome injection, a proprietary formulation with enhanced tissue penetration for local and regional anesthesia with prolonged duration.
How is J0666 administered?
CPT J0666 is administered by a healthcare provider, typically via injection or infusion. Liposomal encapsulation of bupivacaine providing extended anesthesia duration up to 72 hours, used in surgical infiltration, nerve blocks, and regional anesthesia. It is used by anesthesiology, surgery, pain management.
When is CPT J0666 used?
Liposomal encapsulation of bupivacaine providing extended anesthesia duration up to 72 hours, used in surgical infiltration, nerve blocks, and regional anesthesia.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.