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J0878 Daptomycin injection

J Codes (Drugs)

Also known as: Cubicin, daptomycin

Daptomycin injection, a cyclic lipopeptide antibiotic supplied in standard formulation for treatment of serious gram-positive bacterial infections.

In Plain Language

Antibiotic for serious resistant infections

Clinical Context

Used for treatment of Methicillin-resistant Staphylococcus aureus infections, bacteremia, endocarditis, and complicated skin infections.

RVU Information

CPT J0878 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

Infectious DiseaseCritical CareInternal Medicine

Frequently Asked Questions

What is CPT code J0878?

CPT J0878 (Daptomycin injection) is a J Codes (Drugs) code. Daptomycin injection, a cyclic lipopeptide antibiotic supplied in standard formulation for treatment of serious gram-positive bacterial infections.

How is J0878 administered?

CPT J0878 is administered by a healthcare provider, typically via injection or infusion. Used for treatment of Methicillin-resistant Staphylococcus aureus infections, bacteremia, endocarditis, and complicated skin infections. It is used by Infectious Disease, Critical Care, Internal Medicine.

When is CPT J0878 used?

Used for treatment of Methicillin-resistant Staphylococcus aureus infections, bacteremia, endocarditis, and complicated skin infections.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.