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J0879 Difelikefalin, esrd on dialy

J Codes (Drugs)

Also known as: Kapruvia, difelikefalin, KOR agonist

Difelikefalin injection for patients with end-stage renal disease on dialysis, a selective kappa opioid receptor agonist for pruritus management.

In Plain Language

Medicine to relieve itching in kidney disease patients on dialysis

Clinical Context

Used for treatment of uremic pruritus (itching) in patients with end-stage renal disease undergoing dialysis.

RVU Information

CPT J0879 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

NephrologyInternal MedicineDermatology

Frequently Asked Questions

What is CPT code J0879?

CPT J0879 (Difelikefalin, esrd on dialy) is a J Codes (Drugs) code. Difelikefalin injection for patients with end-stage renal disease on dialysis, a selective kappa opioid receptor agonist for pruritus management.

How is J0879 administered?

CPT J0879 is administered by a healthcare provider, typically via injection or infusion. Used for treatment of uremic pruritus (itching) in patients with end-stage renal disease undergoing dialysis. It is used by Nephrology, Internal Medicine, Dermatology.

When is CPT J0879 used?

Used for treatment of uremic pruritus (itching) in patients with end-stage renal disease undergoing dialysis.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.