J1559 Hizentra injection
Also known as: Hizentra, subcutaneous immunoglobulin
Hizentra (human immunoglobulin subcutaneous) injection. A subcutaneous immunoglobulin with high protein concentration for immunodeficiency treatment.
In Plain Language
antibody protection injection; immune replacement therapy
Clinical Context
Used for primary immunodeficiency with subcutaneous administration. High protein concentration allows reduced injection volume and frequency.
RVU Information
CPT J1559 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J1559?
CPT J1559 (Hizentra injection) is a J Codes (Drugs) code. Hizentra (human immunoglobulin subcutaneous) injection. A subcutaneous immunoglobulin with high protein concentration for immunodeficiency treatment.
How is J1559 administered?
CPT J1559 is administered by a healthcare provider, typically via injection or infusion. Used for primary immunodeficiency with subcutaneous administration. High protein concentration allows reduced injection volume and frequency. It is used by Immunology, Internal Medicine, Infectious Diseases.
When is CPT J1559 used?
Used for primary immunodeficiency with subcutaneous administration. High protein concentration allows reduced injection volume and frequency.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.