J2212 Methylnaltrexone injection
Also known as: methylnaltrexone, Relistor
Injection of methylnaltrexone. A peripheral mu-opioid receptor antagonist for opioid-induced constipation.
In Plain Language
opioid constipation reliever; bowel movement stimulator
Clinical Context
Used to treat opioid-induced constipation in patients on chronic opioid therapy. Acts peripherally without affecting opioid-mediated pain relief.
RVU Information
CPT J2212 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J2212?
CPT J2212 (Methylnaltrexone injection) is a J Codes (Drugs) code. Injection of methylnaltrexone. A peripheral mu-opioid receptor antagonist for opioid-induced constipation.
How is J2212 administered?
CPT J2212 is administered by a healthcare provider, typically via injection or infusion. Used to treat opioid-induced constipation in patients on chronic opioid therapy. Acts peripherally without affecting opioid-mediated pain relief. It is used by Gastroenterology, Pain Management, Palliative Care.
When is CPT J2212 used?
Used to treat opioid-induced constipation in patients on chronic opioid therapy. Acts peripherally without affecting opioid-mediated pain relief.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.