J2323 Natalizumab injection
Also known as: natalizumab, Tysabri, alpha-4 integrin antibody
Injection of natalizumab. A monoclonal antibody against alpha-4 integrin for multiple sclerosis and Crohn's disease.
In Plain Language
MS and Crohn's disease medication; immune system blocker
Clinical Context
Used for relapsing-remitting MS and moderate-to-severe Crohn's disease. Natalizumab prevents immune cell infiltration into central nervous system and gut.
RVU Information
CPT J2323 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J2323?
CPT J2323 (Natalizumab injection) is a J Codes (Drugs) code. Injection of natalizumab. A monoclonal antibody against alpha-4 integrin for multiple sclerosis and Crohn's disease.
How is J2323 administered?
CPT J2323 is administered by a healthcare provider, typically via injection or infusion. Used for relapsing-remitting MS and moderate-to-severe Crohn's disease. Natalizumab prevents immune cell infiltration into central nervous system and gut. It is used by Neurology, Gastroenterology, Immunology.
When is CPT J2323 used?
Used for relapsing-remitting MS and moderate-to-severe Crohn's disease. Natalizumab prevents immune cell infiltration into central nervous system and gut.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.