J2425 Palifermin injection
Also known as: palifermin, kepivance
Injection of palifermin (Kepivance), a human keratinocyte growth factor (KGF) used to reduce the incidence and duration of severe oral mucositis in cancer patients.
In Plain Language
mouth sore prevention; growth factor medication
Clinical Context
Administered in oncology settings prior to high-dose chemotherapy and/or radiation to prevent and mitigate painful mouth sores in hematopoietic stem cell transplant recipients.
RVU Information
CPT J2425 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J2425?
CPT J2425 (Palifermin injection) is a J Codes (Drugs) code. Injection of palifermin (Kepivance), a human keratinocyte growth factor (KGF) used to reduce the incidence and duration of severe oral mucositis in cancer patients.
How is J2425 administered?
CPT J2425 is administered by a healthcare provider, typically via injection or infusion. Administered in oncology settings prior to high-dose chemotherapy and/or radiation to prevent and mitigate painful mouth sores in hematopoietic stem cell transplant recipients. It is used by Oncology, Hematology.
When is CPT J2425 used?
Administered in oncology settings prior to high-dose chemotherapy and/or radiation to prevent and mitigate painful mouth sores in hematopoietic stem cell transplant recipients.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.