J2468 Injection, palonosetron (posfrea)
Also known as: palonosetron, posfrea, aloxi
Injection of palonosetron hydrochloride (Posfrea brand), a highly selective 5-HT3 receptor antagonist with longer duration than ondansetron, used for chemotherapy-induced nausea and vomiting (CINV).
In Plain Language
nausea prevention for chemotherapy; long-acting anti-nausea medication
Clinical Context
Administered prophylactically before highly emetogenic chemotherapy and in postoperative nausea and vomiting (PONV) prevention due to its prolonged receptor occupancy.
RVU Information
CPT J2468 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J2468?
CPT J2468 (Injection, palonosetron (posfrea)) is a J Codes (Drugs) code. Injection of palonosetron hydrochloride (Posfrea brand), a highly selective 5-HT3 receptor antagonist with longer duration than ondansetron, used for chemotherapy-induced nausea and vomiting (CINV).
How is J2468 administered?
CPT J2468 is administered by a healthcare provider, typically via injection or infusion. Administered prophylactically before highly emetogenic chemotherapy and in postoperative nausea and vomiting (PONV) prevention due to its prolonged receptor occupancy. It is used by Oncology, Anesthesiology.
When is CPT J2468 used?
Administered prophylactically before highly emetogenic chemotherapy and in postoperative nausea and vomiting (PONV) prevention due to its prolonged receptor occupancy.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.