J2507 Pegloticase injection
Also known as: pegloticase, krystexxa
Injection of pegloticase (Krystexxa), a recombinant uric acid-specific enzyme used to reduce serum uric acid in patients with refractory chronic gout.
In Plain Language
gout treatment; uric acid reducer
Clinical Context
Administered intravenously for patients with severe, refractory gout unresponsive to conventional xanthine oxidase inhibitors and uricosuric agents.
RVU Information
CPT J2507 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J2507?
CPT J2507 (Pegloticase injection) is a J Codes (Drugs) code. Injection of pegloticase (Krystexxa), a recombinant uric acid-specific enzyme used to reduce serum uric acid in patients with refractory chronic gout.
How is J2507 administered?
CPT J2507 is administered by a healthcare provider, typically via injection or infusion. Administered intravenously for patients with severe, refractory gout unresponsive to conventional xanthine oxidase inhibitors and uricosuric agents. It is used by Rheumatology, Internal Medicine.
When is CPT J2507 used?
Administered intravenously for patients with severe, refractory gout unresponsive to conventional xanthine oxidase inhibitors and uricosuric agents.
Track This Code in RVU Edge
Log procedures, calculate wRVUs, and benchmark against MGMA data — all in one app.
CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.