Home
Career Stage
Medical Students Residents Attendings CPT Codes Resources Blog Support

J2543 Piperacillin/tazobactam

J Codes (Drugs)

Also known as: piperacillin/tazobactam, zosyn, pip/tazo

Injection of piperacillin/tazobactam, a combination of extended-spectrum penicillin and beta-lactamase inhibitor for broad-spectrum bacterial infection coverage.

In Plain Language

broad-spectrum antibiotic combination

Clinical Context

Used for empiric therapy of polymicrobial infections, hospital-acquired pneumonia, complex urinary tract infections, and intra-abdominal infections.

RVU Information

CPT J2543 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

Infectious DiseaseSurgeryCritical Care

Frequently Asked Questions

What is CPT code J2543?

CPT J2543 (Piperacillin/tazobactam) is a J Codes (Drugs) code. Injection of piperacillin/tazobactam, a combination of extended-spectrum penicillin and beta-lactamase inhibitor for broad-spectrum bacterial infection coverage.

How is J2543 administered?

CPT J2543 is administered by a healthcare provider, typically via injection or infusion. Used for empiric therapy of polymicrobial infections, hospital-acquired pneumonia, complex urinary tract infections, and intra-abdominal infections. It is used by Infectious Disease, Surgery, Critical Care.

When is CPT J2543 used?

Used for empiric therapy of polymicrobial infections, hospital-acquired pneumonia, complex urinary tract infections, and intra-abdominal infections.

Track This Code in RVU Edge

Log procedures, calculate wRVUs, and benchmark against MGMA data — all in one app.

CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.