J2720 Injection protamine sulfate/10 milligrams
Also known as: protamine, protamine sulfate
Injection of protamine sulfate, per 10 milligrams, used to reverse the anticoagulant effects of heparin or low-molecular-weight heparin.
In Plain Language
blood thinner reversal; heparin antidote
Clinical Context
Used after heparin-based anticoagulation to restore coagulation before surgery or in cases of heparin overdose.
RVU Information
CPT J2720 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J2720?
CPT J2720 (Injection protamine sulfate/10 milligrams) is a J Codes (Drugs) code. Injection of protamine sulfate, per 10 milligrams, used to reverse the anticoagulant effects of heparin or low-molecular-weight heparin.
How is J2720 administered?
CPT J2720 is administered by a healthcare provider, typically via injection or infusion. Used after heparin-based anticoagulation to restore coagulation before surgery or in cases of heparin overdose. It is used by Anesthesiology, Cardiothoracic Surgery, Critical Care.
When is CPT J2720 used?
Used after heparin-based anticoagulation to restore coagulation before surgery or in cases of heparin overdose.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.