J2781 Injection, pegcetacoplan, 1mg
Also known as: pegcetacoplan, empaveli
Injection of pegcetacoplan (Empaveli), 1 milligram, a complement C3 inhibitor used for treatment of paroxysmal nocturnal hemoglobinuria (PNH).
In Plain Language
blood cell protection medication
Clinical Context
Used for treatment of paroxysmal nocturnal hemoglobinuria (PNH) to prevent complement-mediated hemolysis and thrombosis.
RVU Information
CPT J2781 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J2781?
CPT J2781 (Injection, pegcetacoplan, 1mg) is a J Codes (Drugs) code. Injection of pegcetacoplan (Empaveli), 1 milligram, a complement C3 inhibitor used for treatment of paroxysmal nocturnal hemoglobinuria (PNH).
How is J2781 administered?
CPT J2781 is administered by a healthcare provider, typically via injection or infusion. Used for treatment of paroxysmal nocturnal hemoglobinuria (PNH) to prevent complement-mediated hemolysis and thrombosis. It is used by Hematology, Internal Medicine.
When is CPT J2781 used?
Used for treatment of paroxysmal nocturnal hemoglobinuria (PNH) to prevent complement-mediated hemolysis and thrombosis.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.