J3470 Hyaluronidase injection
Also known as: hyaluronidase, hyaluronate lyase, spreading agent
Hyaluronidase injection is an enzyme used as a spreading agent to increase diffusion and absorption of injected drugs and fluids.
In Plain Language
enzyme spreader for other medications
Clinical Context
Used as a spreading agent to enhance diffusion and absorption of concurrently injected medications and intravenous infusions. Applied to subcutaneous, intramuscular, or intravenous administration sites. Enhances drug distribution.
RVU Information
CPT J3470 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J3470?
CPT J3470 (Hyaluronidase injection) is a J Codes (Drugs) code. Hyaluronidase injection is an enzyme used as a spreading agent to increase diffusion and absorption of injected drugs and fluids.
How is J3470 administered?
CPT J3470 is administered by a healthcare provider, typically via injection or infusion. Used as a spreading agent to enhance diffusion and absorption of concurrently injected medications and intravenous infusions. Applied to subcutaneous, intramuscular, or intravenous administration sites. Enhances drug distribution. It is used by Internal Medicine, Anesthesiology, Emergency Medicine.
When is CPT J3470 used?
Used as a spreading agent to enhance diffusion and absorption of concurrently injected medications and intravenous infusions. Applied to subcutaneous, intramuscular, or intravenous administration sites. Enhances drug distribution.
Track This Code in RVU Edge
Log procedures, calculate wRVUs, and benchmark against MGMA data — all in one app.
CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.