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J9227 Injection. isatuximab-irfc 10 milligrams

J Codes (Drugs)

Also known as: isatuximab, Sarclisa

Intravenous injection of isatuximab-irfc, a monoclonal antibody targeting CD38, dosed per 10 milligrams.

In Plain Language

multiple myeloma-targeting antibody; immune-boosting cancer therapy

Clinical Context

Used for relapsed or refractory multiple myeloma in combination with pomalidomide and dexamethasone.

RVU Information

CPT J9227 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

Hematology/OncologyMedical Oncology

Frequently Asked Questions

What is CPT code J9227?

CPT J9227 (Injection. isatuximab-irfc 10 milligrams) is a J Codes (Drugs) code. Intravenous injection of isatuximab-irfc, a monoclonal antibody targeting CD38, dosed per 10 milligrams.

How is J9227 administered?

CPT J9227 is administered by a healthcare provider, typically via injection or infusion. Used for relapsed or refractory multiple myeloma in combination with pomalidomide and dexamethasone. It is used by Hematology/Oncology, Medical Oncology.

When is CPT J9227 used?

Used for relapsed or refractory multiple myeloma in combination with pomalidomide and dexamethasone.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.