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J9228 Ipilimumab injection

J Codes (Drugs)

Also known as: ipilimumab, Yervoy

Intravenous injection of ipilimumab, a monoclonal antibody targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) immune checkpoint.

In Plain Language

immune checkpoint inhibitor; cancer-fighting immune therapy

Clinical Context

Used for melanoma and other advanced cancers by blocking CTLA-4 checkpoint to enhance T-cell immune response.

RVU Information

CPT J9228 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

OncologyImmunotherapy

Frequently Asked Questions

What is CPT code J9228?

CPT J9228 (Ipilimumab injection) is a J Codes (Drugs) code. Intravenous injection of ipilimumab, a monoclonal antibody targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) immune checkpoint.

How is J9228 administered?

CPT J9228 is administered by a healthcare provider, typically via injection or infusion. Used for melanoma and other advanced cancers by blocking CTLA-4 checkpoint to enhance T-cell immune response. It is used by Oncology, Immunotherapy.

When is CPT J9228 used?

Used for melanoma and other advanced cancers by blocking CTLA-4 checkpoint to enhance T-cell immune response.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.