J9271 Injection pembrolizumab
Also known as: pembrolizumab, Keytruda
Injection of pembrolizumab, a programmed cell death protein 1 (PD-1) monoclonal antibody. Immune checkpoint inhibitor for multiple malignancies.
In Plain Language
immunotherapy injection; cancer immune treatment
Clinical Context
First-line therapy for many cancers including melanoma, non-small cell lung cancer, and head/neck cancers. Used as monotherapy and in combination regimens.
RVU Information
CPT J9271 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.
Billing & Documentation
J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.
Specialties
Frequently Asked Questions
What is CPT code J9271?
CPT J9271 (Injection pembrolizumab) is a J Codes (Drugs) code. Injection of pembrolizumab, a programmed cell death protein 1 (PD-1) monoclonal antibody. Immune checkpoint inhibitor for multiple malignancies.
How is J9271 administered?
CPT J9271 is administered by a healthcare provider, typically via injection or infusion. First-line therapy for many cancers including melanoma, non-small cell lung cancer, and head/neck cancers. Used as monotherapy and in combination regimens. It is used by Oncology, Dermatology, Pulmonology.
When is CPT J9271 used?
First-line therapy for many cancers including melanoma, non-small cell lung cancer, and head/neck cancers. Used as monotherapy and in combination regimens.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.