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J9381 Injection teplizumab mzwv 5 micrograms

J Codes (Drugs)

Also known as: teplizumab, Provysio

Injection of teplizumab mzwv, 5 microgram. A T-cell receptor-engaging anti-CD3 monoclonal antibody for type 1 diabetes prevention.

In Plain Language

diabetes prevention injection; immune tolerance induction

Clinical Context

Used to delay onset of type 1 diabetes in at-risk individuals. CD3-engaging antibody inducing immune tolerance.

RVU Information

CPT J9381 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

J-codes represent drugs administered by a healthcare provider (not self-administered). Documentation must include the drug name, dosage, route of administration, and medical necessity. Most payers require the National Drug Code (NDC) on the claim. Bill the appropriate administration code (96365-96379) in addition to the drug code.

Specialties

EndocrinologyImmunologyInternal Medicine

Frequently Asked Questions

What is CPT code J9381?

CPT J9381 (Injection teplizumab mzwv 5 micrograms) is a J Codes (Drugs) code. Injection of teplizumab mzwv, 5 microgram. A T-cell receptor-engaging anti-CD3 monoclonal antibody for type 1 diabetes prevention.

How is J9381 administered?

CPT J9381 is administered by a healthcare provider, typically via injection or infusion. Used to delay onset of type 1 diabetes in at-risk individuals. CD3-engaging antibody inducing immune tolerance. It is used by Endocrinology, Immunology, Internal Medicine.

When is CPT J9381 used?

Used to delay onset of type 1 diabetes in at-risk individuals. CD3-engaging antibody inducing immune tolerance.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.