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95857 Cholinesterase challenge

Medicine

Also known as: Tensilon test, edrophonium test, anticholinesterase test

Cholinesterase inhibitor challenge test; for evaluation of myasthenia gravis.

In Plain Language

myasthenia test

Clinical Context

Diagnostic test using anticholinesterase agents to confirm myasthenia gravis. Measures muscle strength improvement with medication challenge.

RVU Breakdown

Work RVU0.52
Total RVU0.52

Est. Medicare Payment

$17.37

National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).

Billing & Documentation

Medicine section codes cover a wide range of non-surgical services. Documentation should include the clinical indication, procedure details, interpretation (if applicable), and any patient-specific findings.

How This Code Compares

With a work RVU of 0.52, this code ranks in the 36th percentile among Medicine codes — 1.5x below the median (0.78). The highest wRVU in this category is 23.92.

Specialties

Neurology

Frequently Asked Questions

What is CPT code 95857?

CPT 95857 (Cholinesterase challenge) is a Medicine code. Cholinesterase inhibitor challenge test; for evaluation of myasthenia gravis.

Who uses CPT code 95857?

CPT 95857 is used by Neurology. Diagnostic test using anticholinesterase agents to confirm myasthenia gravis. Measures muscle strength improvement with medication challenge.

When is CPT 95857 used?

Diagnostic test using anticholinesterase agents to confirm myasthenia gravis. Measures muscle strength improvement with medication challenge.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.