96405 Chemotherapy intralesional up to 7
Also known as: intralesional chemo, lesion injection, skin lesion chemo
Chemotherapy intralesional injection into lesions (up to 7 lesions).
In Plain Language
cancer medicine injected into sore
Clinical Context
Direct intralesional injection of chemotherapy agents into skin cancers or other lesions for localized treatment; limited to up to 7 lesions.
RVU Breakdown
| Work RVU | 0.52 |
| Total RVU | 0.52 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Medicine section codes cover a wide range of non-surgical services. This code has a 0-day global period, meaning pre- and post-operative E&M visits are billable separately on the same day. Documentation should include the clinical indication, procedure details, interpretation (if applicable), and any patient-specific findings.
How This Code Compares
With a work RVU of 0.52, this code ranks in the 36th percentile among Medicine codes — 1.5x below the median (0.78). The highest wRVU in this category is 23.92.
Specialties
Frequently Asked Questions
What is CPT code 96405?
CPT 96405 (Chemotherapy intralesional up to 7) is a Medicine code. Chemotherapy intralesional injection into lesions (up to 7 lesions).
Who uses CPT code 96405?
CPT 96405 is used by Dermatology, Oncology. Direct intralesional injection of chemotherapy agents into skin cancers or other lesions for localized treatment; limited to up to 7 lesions.
When is CPT 96405 used?
Direct intralesional injection of chemotherapy agents into skin cancers or other lesions for localized treatment; limited to up to 7 lesions.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.