96450 Chemotherapy into cns
Also known as: Intrathecal chemo, Central nervous system chemo, Spinal chemotherapy
Administration of chemotherapy agents by intrathecal, intraventricular, or intra-central nervous system injection directly into cerebrospinal fluid. Used to treat malignancies involving the brain or spinal cord.
Clinical Context
Indicated for acute leukemia prophylaxis, central nervous system lymphoma, and metastatic cancers to brain/meninges. Requires careful technique to deliver chemotherapy across blood-brain barrier.
RVU Breakdown
| Work RVU | 1.53 |
| Practice Expense RVU | 3.15 |
| Malpractice RVU | 0.14 |
| Total RVU | 4.82 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Specialties
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.