81221 Cftr gene known fam variants
Also known as: CFTR familial variant testing, CFTR targeted analysis
Targeted mutation analysis of the CFTR gene to identify known familial variants associated with Cystic Fibrosis.
In Plain Language
cystic fibrosis gene test; family mutation detection
Clinical Context
Used to identify known CFTR pathogenic variants in family members of affected individuals for carrier status determination and genetic counseling.
RVU Information
CPT 81221 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 81221?
CPT 81221 (Cftr gene known fam variants) is a Pathology & Lab code. Targeted mutation analysis of the CFTR gene to identify known familial variants associated with Cystic Fibrosis.
Who uses CPT code 81221?
CPT 81221 is used by Genetics, Pulmonology, Pathology. Used to identify known CFTR pathogenic variants in family members of affected individuals for carrier status determination and genetic counseling.
When is CPT 81221 used?
Used to identify known CFTR pathogenic variants in family members of affected individuals for carrier status determination and genetic counseling.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.