81226 Cyp2d6 gene com variants
Also known as: CYP2D6 pharmacogenetic panel, CYP2D6 variant testing
Molecular analysis of the CYP2D6 gene to identify common pharmacogenetic variants affecting drug metabolism of numerous medications.
In Plain Language
medicine metabolism gene test; drug response genetic testing
Clinical Context
Used to guide dosing and selection of medications metabolized by CYP2D6 (e.g., antipsychotics, antidepressants, codeine) for therapeutic optimization.
RVU Information
CPT 81226 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 81226?
CPT 81226 (Cyp2d6 gene com variants) is a Pathology & Lab code. Molecular analysis of the CYP2D6 gene to identify common pharmacogenetic variants affecting drug metabolism of numerous medications.
Who uses CPT code 81226?
CPT 81226 is used by Pathology, Pharmacology, Clinical Genetics. Used to guide dosing and selection of medications metabolized by CYP2D6 (e.g., antipsychotics, antidepressants, codeine) for therapeutic optimization.
When is CPT 81226 used?
Used to guide dosing and selection of medications metabolized by CYP2D6 (e.g., antipsychotics, antidepressants, codeine) for therapeutic optimization.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.