81259 Hba1/hba2 full gene sequence
Also known as: HBA alpha gene sequencing, alpha globin full sequencing
Hemoglobin Alpha 1 and Alpha 2 genes full gene sequence analysis including all exons and introns to identify structural variants and mutations associated with hemoglobinopathies.
In Plain Language
Complete red blood cell protein gene test; Alpha globin chain genetic analysis
Clinical Context
Used to diagnose alpha thalassemia and other hemoglobinopathies where alpha globin chain synthesis is affected. Essential for carrier screening and prenatal diagnosis.
RVU Information
CPT 81259 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 81259?
CPT 81259 (Hba1/hba2 full gene sequence) is a Pathology & Lab code. Hemoglobin Alpha 1 and Alpha 2 genes full gene sequence analysis including all exons and introns to identify structural variants and mutations associated with hemoglobinopathies.
Who uses CPT code 81259?
CPT 81259 is used by Pathology, Hematology, Genetics. Used to diagnose alpha thalassemia and other hemoglobinopathies where alpha globin chain synthesis is affected. Essential for carrier screening and prenatal diagnosis.
When is CPT 81259 used?
Used to diagnose alpha thalassemia and other hemoglobinopathies where alpha globin chain synthesis is affected. Essential for carrier screening and prenatal diagnosis.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.