81275 Kras gene variants exon 2
Also known as: KRAS exon 2 mutation analysis, codon 12/13 KRAS testing
KRAS proto-oncogene GTPase (KRAS) gene variant analysis focusing on exon 2 mutations commonly associated with pancreatic and colorectal cancers.
In Plain Language
Pancreatic cancer mutation test; Colorectal cancer genetic marker
Clinical Context
Detects common KRAS exon 2 mutations (G12, G13) in pancreatic, colorectal, and lung cancers to predict response to targeted therapies and anti-EGFR agents.
RVU Information
CPT 81275 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 81275?
CPT 81275 (Kras gene variants exon 2) is a Pathology & Lab code. KRAS proto-oncogene GTPase (KRAS) gene variant analysis focusing on exon 2 mutations commonly associated with pancreatic and colorectal cancers.
Who uses CPT code 81275?
CPT 81275 is used by Pathology, Oncology, Gastroenterology. Detects common KRAS exon 2 mutations (G12, G13) in pancreatic, colorectal, and lung cancers to predict response to targeted therapies and anti-EGFR agents.
When is CPT 81275 used?
Detects common KRAS exon 2 mutations (G12, G13) in pancreatic, colorectal, and lung cancers to predict response to targeted therapies and anti-EGFR agents.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.