Home
Career Stage
Medical Students Residents Attendings CPT Codes Resources Blog Support

81299 Msh6 gene known variants

Pathology & Lab

Also known as: MSH6 familial variant testing, MSH6 family screening

Mutator S Homolog 6 (MSH6) gene analysis for known familial variants to facilitate family member screening in Lynch syndrome.

In Plain Language

Family Lynch syndrome test; Inherited cancer genetic testing

Clinical Context

Targeted MSH6 testing of family members for previously identified variants to improve diagnostic efficiency and cancer surveillance.

RVU Information

CPT 81299 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.

Specialties

PathologyOncologyGastroenterology

Frequently Asked Questions

What is CPT code 81299?

CPT 81299 (Msh6 gene known variants) is a Pathology & Lab code. Mutator S Homolog 6 (MSH6) gene analysis for known familial variants to facilitate family member screening in Lynch syndrome.

Who uses CPT code 81299?

CPT 81299 is used by Pathology, Oncology, Gastroenterology. Targeted MSH6 testing of family members for previously identified variants to improve diagnostic efficiency and cancer surveillance.

When is CPT 81299 used?

Targeted MSH6 testing of family members for previously identified variants to improve diagnostic efficiency and cancer surveillance.

Track This Code in RVU Edge

Log procedures, calculate wRVUs, and benchmark against national data — all in one app.

CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.