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81310 Npm1 gene

Pathology & Lab

Also known as: NPM1 mutation test, acute myeloid leukemia genetic marker

Nucleophosmin 1 (NPM1) gene mutation analysis to detect alterations associated with acute myeloid leukemia.

In Plain Language

Blood cancer mutation test; Leukemia genetic marker

Clinical Context

Detects NPM1 mutations present in approximately 30% of acute myeloid leukemias. Important for diagnosis, prognosis, and minimal residual disease monitoring.

RVU Information

CPT 81310 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.

Specialties

PathologyHematologyOncology

Frequently Asked Questions

What is CPT code 81310?

CPT 81310 (Npm1 gene) is a Pathology & Lab code. Nucleophosmin 1 (NPM1) gene mutation analysis to detect alterations associated with acute myeloid leukemia.

Who uses CPT code 81310?

CPT 81310 is used by Pathology, Hematology, Oncology. Detects NPM1 mutations present in approximately 30% of acute myeloid leukemias. Important for diagnosis, prognosis, and minimal residual disease monitoring.

When is CPT 81310 used?

Detects NPM1 mutations present in approximately 30% of acute myeloid leukemias. Important for diagnosis, prognosis, and minimal residual disease monitoring.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.