Home
Career Stage
Medical Students Residents Attendings CPT Codes Resources Blog Support

81316 Pml/raralpha 1 breakpoint

Pathology & Lab

Also known as: PML/RARA single breakpoint test, APL translocation variant

Promyelocytic Leukemia protein (PML) and Retinoic Acid Receptor Alpha (RARA) gene single breakpoint analysis for acute promyelocytic leukemia.

In Plain Language

APL cancer translocation detection; Leukemia variant analysis

Clinical Context

Detects variant PML/RARA breakpoints in acute promyelocytic leukemia when common breakpoint analysis is negative.

RVU Information

CPT 81316 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.

Specialties

PathologyHematologyOncology

Frequently Asked Questions

What is CPT code 81316?

CPT 81316 (Pml/raralpha 1 breakpoint) is a Pathology & Lab code. Promyelocytic Leukemia protein (PML) and Retinoic Acid Receptor Alpha (RARA) gene single breakpoint analysis for acute promyelocytic leukemia.

Who uses CPT code 81316?

CPT 81316 is used by Pathology, Hematology, Oncology. Detects variant PML/RARA breakpoints in acute promyelocytic leukemia when common breakpoint analysis is negative.

When is CPT 81316 used?

Detects variant PML/RARA breakpoints in acute promyelocytic leukemia when common breakpoint analysis is negative.

Track This Code in RVU Edge

Log procedures, calculate wRVUs, and benchmark against national data — all in one app.

CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.