Home
Career Stage
Medical Students Residents Attendings CPT Codes Resources Blog Support

81451 Hl neo gsap 5-50 rna alys

Pathology & Lab

Also known as: high-level tumor RNA panel

High-level oncology gene analysis panel for 5-50 genes using RNA analysis only.

In Plain Language

detailed cancer gene expression test

Clinical Context

RNA-based comprehensive analysis for somatic mutations and expression patterns; useful for gene fusion detection and treatment selection.

RVU Information

CPT 81451 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.

Specialties

oncologymolecular pathologypathology

Frequently Asked Questions

What is CPT code 81451?

CPT 81451 (Hl neo gsap 5-50 rna alys) is a Pathology & Lab code. High-level oncology gene analysis panel for 5-50 genes using RNA analysis only.

Who uses CPT code 81451?

CPT 81451 is used by oncology, molecular pathology, pathology. RNA-based comprehensive analysis for somatic mutations and expression patterns; useful for gene fusion detection and treatment selection.

When is CPT 81451 used?

RNA-based comprehensive analysis for somatic mutations and expression patterns; useful for gene fusion detection and treatment selection.

Track This Code in RVU Edge

Log procedures, calculate wRVUs, and benchmark against national data — all in one app.

CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.