81459 So neo gsap dna/dna & rna
Also known as: comprehensive somatic profiling, tumor DNA/RNA testing
Somatic oncology gene sequence analysis with DNA and RNA analysis.
In Plain Language
complete genetic test of cancer
Clinical Context
Combined DNA sequencing and RNA expression analysis of somatic mutations for comprehensive tumor profiling.
RVU Information
CPT 81459 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 81459?
CPT 81459 (So neo gsap dna/dna & rna) is a Pathology & Lab code. Somatic oncology gene sequence analysis with DNA and RNA analysis.
Who uses CPT code 81459?
CPT 81459 is used by oncology, molecular pathology, pathology. Combined DNA sequencing and RNA expression analysis of somatic mutations for comprehensive tumor profiling.
When is CPT 81459 used?
Combined DNA sequencing and RNA expression analysis of somatic mutations for comprehensive tumor profiling.
Track This Code in RVU Edge
Log procedures, calculate wRVUs, and benchmark against national data — all in one app.
CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.