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81540 Oncology tumor unknown origin

Pathology & Lab

Also known as: cancer of unknown primary, tumor of unknown origin test

Oncology (tumor of unknown origin) classification using gene expression profiling.

In Plain Language

genetic test to find where cancer came from

Clinical Context

Gene expression-based profiling to identify tissue of origin in metastatic cancers with unknown primary site.

RVU Information

CPT 81540 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.

Specialties

oncologymolecular pathologypathology

Frequently Asked Questions

What is CPT code 81540?

CPT 81540 (Oncology tumor unknown origin) is a Pathology & Lab code. Oncology (tumor of unknown origin) classification using gene expression profiling.

Who uses CPT code 81540?

CPT 81540 is used by oncology, molecular pathology, pathology. Gene expression-based profiling to identify tissue of origin in metastatic cancers with unknown primary site.

When is CPT 81540 used?

Gene expression-based profiling to identify tissue of origin in metastatic cancers with unknown primary site.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.