Home
Career Stage
Medical Students Residents Attendings CPT Codes Resources Blog Support

82105 Alpha-fetoprotein serum

Pathology & Lab

Also known as: serum AFP, alpha-fetoprotein, cancer tumor marker

Immunoassay measurement of alpha-fetoprotein in serum used for prenatal screening and hepatocellular carcinoma surveillance.

In Plain Language

birth defect screening test; liver cancer marker; fetal abnormality test

Clinical Context

Elevated in hepatocellular carcinoma, germ cell tumors, and neural tube defects; serial measurements track tumor burden and treatment response.

RVU Information

CPT 82105 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.

Specialties

PathologyOncologyObstetrics

Frequently Asked Questions

What is CPT code 82105?

CPT 82105 (Alpha-fetoprotein serum) is a Pathology & Lab code. Immunoassay measurement of alpha-fetoprotein in serum used for prenatal screening and hepatocellular carcinoma surveillance.

Who uses CPT code 82105?

CPT 82105 is used by Pathology, Oncology, Obstetrics. Elevated in hepatocellular carcinoma, germ cell tumors, and neural tube defects; serial measurements track tumor burden and treatment response.

When is CPT 82105 used?

Elevated in hepatocellular carcinoma, germ cell tumors, and neural tube defects; serial measurements track tumor burden and treatment response.

Track This Code in RVU Edge

Log procedures, calculate wRVUs, and benchmark against national data — all in one app.

CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.