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82261 Assay of biotinidase

Pathology & Lab

Also known as: biotinidase assay, biotin deficiency test, metabolic screening

Enzymatic assay measuring biotinidase activity in serum or dried blood spot to screen for biotinidase deficiency.

In Plain Language

biotin enzyme test; vitamin deficiency screening; genetic metabolic test

Clinical Context

Screens for biotinidase deficiency causing neurological impairment and hearing loss; detected on newborn screening.

RVU Information

CPT 82261 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.

Specialties

PathologyGeneticsPediatrics

Frequently Asked Questions

What is CPT code 82261?

CPT 82261 (Assay of biotinidase) is a Pathology & Lab code. Enzymatic assay measuring biotinidase activity in serum or dried blood spot to screen for biotinidase deficiency.

Who uses CPT code 82261?

CPT 82261 is used by Pathology, Genetics, Pediatrics. Screens for biotinidase deficiency causing neurological impairment and hearing loss; detected on newborn screening.

When is CPT 82261 used?

Screens for biotinidase deficiency causing neurological impairment and hearing loss; detected on newborn screening.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.