84681 Assay of c-peptide
Also known as: C-peptide test, connecting peptide
Quantitative assay of C-peptide (connecting peptide) in serum or plasma, measured by immunoassay to assess endogenous insulin secretion independent of exogenous insulin administration.
In Plain Language
insulin production test; pancreas insulin secretion test
Clinical Context
Differentiates type 1 from type 2 diabetes, evaluates insulin secretory capacity in diabetics, and detects hypoglycemia from surreptitious insulin injection versus sulfonylurea use.
RVU Information
CPT 84681 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 84681?
CPT 84681 (Assay of c-peptide) is a Pathology & Lab code. Quantitative assay of C-peptide (connecting peptide) in serum or plasma, measured by immunoassay to assess endogenous insulin secretion independent of exogenous insulin administration.
Who uses CPT code 84681?
CPT 84681 is used by Clinical Pathology, Endocrinology, Internal Medicine. Differentiates type 1 from type 2 diabetes, evaluates insulin secretory capacity in diabetics, and detects hypoglycemia from surreptitious insulin injection versus sulfonylurea use.
When is CPT 84681 used?
Differentiates type 1 from type 2 diabetes, evaluates insulin secretory capacity in diabetics, and detects hypoglycemia from surreptitious insulin injection versus sulfonylurea use.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.