85390 Fibrinolysins screening i & r
Also known as: fibrinolysin screen, plasmin activity
Screening and investigation (confirmation) assay for fibrinolysin (plasmin) activity in plasma using substrate methodology to detect primary hyperfibrinolysis.
In Plain Language
fibrin-dissolving enzyme test; plasmin activity screening
Clinical Context
Screens for excessive fibrinolytic activity in amyloidosis, liver disease, or malignancy; detects plasmin-mediated fibrin degradation independent of thrombin generation.
RVU Breakdown
| Work RVU | 0.75 |
| Total RVU | 0.75 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
With a work RVU of 0.75, this code ranks in the 64th percentile among Pathology & Lab codes — 1.1x the median (0.68). The highest wRVU in this category is 2.78.
Specialties
Frequently Asked Questions
What is CPT code 85390?
CPT 85390 (Fibrinolysins screening i & r) is a Pathology & Lab code. Screening and investigation (confirmation) assay for fibrinolysin (plasmin) activity in plasma using substrate methodology to detect primary hyperfibrinolysis.
Who uses CPT code 85390?
CPT 85390 is used by Clinical Pathology, Coagulation, Hematology. Screens for excessive fibrinolytic activity in amyloidosis, liver disease, or malignancy; detects plasmin-mediated fibrin degradation independent of thrombin generation.
When is CPT 85390 used?
Screens for excessive fibrinolytic activity in amyloidosis, liver disease, or malignancy; detects plasmin-mediated fibrin degradation independent of thrombin generation.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.