Home
Career Stage
Medical Students Residents Attendings CPT Codes Resources Blog Support

85421 Fibrinolytic plasminogen

Pathology & Lab

Also known as: plasminogen antigen, immunologic plasminogen

Measurement of plasminogen antigen concentration in plasma using immunoassay to quantify plasminogen protein level independent of functional activity.

In Plain Language

plasminogen protein level; immunologic plasminogen measurement

Clinical Context

Detects discordance between plasminogen activity and antigen; identifies dysfunctional plasminogen or measuring antigen in thrombotic disease.

RVU Information

CPT 85421 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.

Specialties

Clinical PathologyCoagulationHematology

Frequently Asked Questions

What is CPT code 85421?

CPT 85421 (Fibrinolytic plasminogen) is a Pathology & Lab code. Measurement of plasminogen antigen concentration in plasma using immunoassay to quantify plasminogen protein level independent of functional activity.

Who uses CPT code 85421?

CPT 85421 is used by Clinical Pathology, Coagulation, Hematology. Detects discordance between plasminogen activity and antigen; identifies dysfunctional plasminogen or measuring antigen in thrombotic disease.

When is CPT 85421 used?

Detects discordance between plasminogen activity and antigen; identifies dysfunctional plasminogen or measuring antigen in thrombotic disease.

Track This Code in RVU Edge

Log procedures, calculate wRVUs, and benchmark against national data — all in one app.

CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.