86235 Nuclear antigen antibody
Also known as: ENA panel, extractable nuclear antigens
Extractable nuclear antigen (ENA) antibody test measures autoantibodies against soluble nuclear antigens (Ro/SSA, La/SSB, Sm, RNP), identifying specific connective tissue disease autoantibodies.
In Plain Language
Connective tissue disease test; Antibody pattern identification
Clinical Context
Reflex test when ANA is positive to identify specific autoimmune diseases (Sjögren, SLE with anti-Sm, lupus with anti-RNP) and predict clinical manifestations.
RVU Information
CPT 86235 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 86235?
CPT 86235 (Nuclear antigen antibody) is a Pathology & Lab code. Extractable nuclear antigen (ENA) antibody test measures autoantibodies against soluble nuclear antigens (Ro/SSA, La/SSB, Sm, RNP), identifying specific connective tissue disease autoantibodies.
Who uses CPT code 86235?
CPT 86235 is used by Rheumatology, Immunology, Clinical Pathology. Reflex test when ANA is positive to identify specific autoimmune diseases (Sjögren, SLE with anti-Sm, lupus with anti-RNP) and predict clinical manifestations.
When is CPT 86235 used?
Reflex test when ANA is positive to identify specific autoimmune diseases (Sjögren, SLE with anti-Sm, lupus with anti-RNP) and predict clinical manifestations.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.