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86255 Fluorescent antibody screening

Pathology & Lab

Also known as: Fluorescent antibody screen, FA screen

Fluorescent antibody screen qualitatively detects antibodies using immunofluorescence microscopy, screening for various infectious agents or autoimmune antibodies.

In Plain Language

Fluorescent antibody test; Glowing antibody detection

Clinical Context

Used for initial screening of antibodies to viral agents (Legionella, Bordetella, Chlamydia) and various autoantibodies using fluorescent microscopy.

RVU Breakdown

Work RVU0.37
Total RVU0.37

Est. Medicare Payment

$12.36

National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

With a work RVU of 0.37, this code ranks in the 29th percentile among Pathology & Lab codes — 1.8x below the median (0.68). The highest wRVU in this category is 2.78.

Specialties

MicrobiologyImmunologyClinical Pathology

Frequently Asked Questions

What is CPT code 86255?

CPT 86255 (Fluorescent antibody screening) is a Pathology & Lab code. Fluorescent antibody screen qualitatively detects antibodies using immunofluorescence microscopy, screening for various infectious agents or autoimmune antibodies.

Who uses CPT code 86255?

CPT 86255 is used by Microbiology, Immunology, Clinical Pathology. Used for initial screening of antibodies to viral agents (Legionella, Bordetella, Chlamydia) and various autoantibodies using fluorescent microscopy.

When is CPT 86255 used?

Used for initial screening of antibodies to viral agents (Legionella, Bordetella, Chlamydia) and various autoantibodies using fluorescent microscopy.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.