86305 Human epididymis protein 4
Also known as: HE4, human epididymis protein 4
Human epididymis protein 4 (HE4) immunoassay quantitatively measures tumor-associated antigen useful for ovarian cancer detection and monitoring.
In Plain Language
Ovarian cancer protein; Advanced tumor marker
Clinical Context
Increasingly used with CA 125 to improve ovarian cancer detection. Better specificity than CA 125 alone and useful in patients with borderline CA 125 elevations.
RVU Information
CPT 86305 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 86305?
CPT 86305 (Human epididymis protein 4) is a Pathology & Lab code. Human epididymis protein 4 (HE4) immunoassay quantitatively measures tumor-associated antigen useful for ovarian cancer detection and monitoring.
Who uses CPT code 86305?
CPT 86305 is used by Oncology, Gynecology, Clinical Pathology. Increasingly used with CA 125 to improve ovarian cancer detection. Better specificity than CA 125 alone and useful in patients with borderline CA 125 elevations.
When is CPT 86305 used?
Increasingly used with CA 125 to improve ovarian cancer detection. Better specificity than CA 125 alone and useful in patients with borderline CA 125 elevations.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.