86343 Leukocyte histamine release
Also known as: Histamine release test, basophil activation test
Leukocyte histamine release test measures histamine release from basophils and mast cells in response to allergen exposure, assessing allergic sensitization.
In Plain Language
Allergy cell response test; Immune cell activation test
Clinical Context
Used to assess basophil activation and degranulation in response to allergens. More physiologic assessment of allergic response than skin testing.
RVU Information
CPT 86343 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.
Specialties
Frequently Asked Questions
What is CPT code 86343?
CPT 86343 (Leukocyte histamine release) is a Pathology & Lab code. Leukocyte histamine release test measures histamine release from basophils and mast cells in response to allergen exposure, assessing allergic sensitization.
Who uses CPT code 86343?
CPT 86343 is used by Allergy/Immunology, Immunology, Clinical Pathology. Used to assess basophil activation and degranulation in response to allergens. More physiologic assessment of allergic response than skin testing.
When is CPT 86343 used?
Used to assess basophil activation and degranulation in response to allergens. More physiologic assessment of allergic response than skin testing.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.