Home
Career Stage
Medical Students Residents Attendings CPT Codes Resources Blog Support

86825 Hla x-math non-cytotoxic

Pathology & Lab

Also known as: HLA non-cytotoxic crossmatch, Non-complement crossmatch, Flow crossmatch

Human leukocyte antigen cross-match using non-cytotoxic methodology to detect donor-specific antibodies. Identifies antibodies causing graft injury.

In Plain Language

Advanced transplant antibody test; Graft damage risk test

Clinical Context

Used to detect immunoglobulin G antibodies that may not activate complement. More sensitive than traditional cytotoxic crossmatch, particularly important in living donor kidney transplantation.

RVU Information

CPT 86825 does not have a physician work RVU assigned by CMS. Reimbursement for this code is determined by payer-specific fee schedules.

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

This code has a work RVU of 0.00, meaning it does not have a physician work component assigned by CMS. In the Pathology & Lab category, 94% of codes share this characteristic.

Specialties

PathologyImmunologyTransplantation

Frequently Asked Questions

What is CPT code 86825?

CPT 86825 (Hla x-math non-cytotoxic) is a Pathology & Lab code. Human leukocyte antigen cross-match using non-cytotoxic methodology to detect donor-specific antibodies. Identifies antibodies causing graft injury.

Who uses CPT code 86825?

CPT 86825 is used by Pathology, Immunology, Transplantation. Used to detect immunoglobulin G antibodies that may not activate complement. More sensitive than traditional cytotoxic crossmatch, particularly important in living donor kidney transplantation.

When is CPT 86825 used?

Used to detect immunoglobulin G antibodies that may not activate complement. More sensitive than traditional cytotoxic crossmatch, particularly important in living donor kidney transplantation.

Track This Code in RVU Edge

Log procedures, calculate wRVUs, and benchmark against national data — all in one app.

CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.