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88121 Cytp urine 3-5 probes cmptr

Pathology & Lab

Also known as: urine FISH computer, cytopath urine FISH auto

Cytopathology analysis of urine specimen using 3 to 5 fluorescence in situ hybridization probes with computer-assisted analysis.

In Plain Language

urine chromosome counting computer test

Clinical Context

Computerized microscopic examination of urine using multiple fluorescent probes for bladder cancer detection.

RVU Breakdown

Work RVU0.98
Total RVU0.98

Est. Medicare Payment

$32.73

National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).

Billing & Documentation

Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.

How This Code Compares

With a work RVU of 0.98, this code ranks in the 79th percentile among Pathology & Lab codes — 1.5x the median (0.68). The highest wRVU in this category is 2.78.

Specialties

cytopathologyoncologyurology

Frequently Asked Questions

What is CPT code 88121?

CPT 88121 (Cytp urine 3-5 probes cmptr) is a Pathology & Lab code. Cytopathology analysis of urine specimen using 3 to 5 fluorescence in situ hybridization probes with computer-assisted analysis.

Who uses CPT code 88121?

CPT 88121 is used by cytopathology, oncology, urology. Computerized microscopic examination of urine using multiple fluorescent probes for bladder cancer detection.

When is CPT 88121 used?

Computerized microscopic examination of urine using multiple fluorescent probes for bladder cancer detection.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.