88311 Decalcify tissue
Also known as: decalcify tissue, bone demineralization, decalcification
Processing of tissue specimens using decalcification procedures to remove mineral deposits before routine histologic processing.
In Plain Language
bone softening for examination; mineral removal from tissue
Clinical Context
Required for bone specimens, calcified lesions, or tissues containing mineral deposits to allow proper sectioning and microscopic examination.
RVU Breakdown
| Work RVU | 0.23 |
| Total RVU | 0.23 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
With a work RVU of 0.23, this code ranks in the 5th percentile among Pathology & Lab codes — 2.9x below the median (0.68). The highest wRVU in this category is 2.78.
Specialties
Frequently Asked Questions
What is CPT code 88311?
CPT 88311 (Decalcify tissue) is a Pathology & Lab code. Processing of tissue specimens using decalcification procedures to remove mineral deposits before routine histologic processing.
Who uses CPT code 88311?
CPT 88311 is used by Surgical Pathology, Laboratory. Required for bone specimens, calcified lesions, or tissues containing mineral deposits to allow proper sectioning and microscopic examination.
When is CPT 88311 used?
Required for bone specimens, calcified lesions, or tissues containing mineral deposits to allow proper sectioning and microscopic examination.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.