88342 Imhchem/imcytchm first antb
Also known as: immunochemistry first antibody, IHC first antibody
Immunohistochemistry or immunocytochemistry for the first antibody applied to tissue specimen for diagnostic assessment.
In Plain Language
immune marker staining for diagnosis; antibody staining of tissue
Clinical Context
Initial immunochemical staining to identify antigens in tissue; commonly used in cancer diagnosis and classification.
RVU Breakdown
| Work RVU | 0.68 |
| Total RVU | 0.68 |
Est. Medicare Payment
National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).
Billing & Documentation
Lab and pathology codes require an order from the treating provider with clinical indication. For molecular pathology and genetic testing, document the specific analytes tested and clinical rationale.
How This Code Compares
With a work RVU of 0.68, this code ranks in the 53rd percentile among Pathology & Lab codes — 1.0x the median (0.68). The highest wRVU in this category is 2.78.
Specialties
Frequently Asked Questions
What is CPT code 88342?
CPT 88342 (Imhchem/imcytchm first antb) is a Pathology & Lab code. Immunohistochemistry or immunocytochemistry for the first antibody applied to tissue specimen for diagnostic assessment.
Who uses CPT code 88342?
CPT 88342 is used by Pathology, Oncology. Initial immunochemical staining to identify antigens in tissue; commonly used in cancer diagnosis and classification.
When is CPT 88342 used?
Initial immunochemical staining to identify antigens in tissue; commonly used in cancer diagnosis and classification.
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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.