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S3850 Gene test sickle cell

S Codes

Also known as: sickle cell gene test, hemoglobinopathy testing

Genetic testing for mutations in the HBB gene causing sickle cell disease, an inherited hemoglobin disorder affecting red blood cell shape and function.

In Plain Language

genetic test for sickle cell disease; inherited blood disease gene test

Clinical Context

Used in hematology, pediatrics, and newborn screening for diagnosis of sickle cell disease and carrier identification.

RVU Information

CPT S3850 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

S-codes are used by private payers (not Medicare) for services without a standard CPT or HCPCS code. Coverage varies significantly between insurers. Verify payer acceptance before billing and document medical necessity thoroughly.

Specialties

HematologyPediatricsLaboratory Medicine

Frequently Asked Questions

What is CPT code S3850?

CPT S3850 (Gene test sickle cell) is a S Codes code. Genetic testing for mutations in the HBB gene causing sickle cell disease, an inherited hemoglobin disorder affecting red blood cell shape and function.

Is S3850 covered by insurance?

S3850 is a temporary HCPCS code. Coverage varies by payer and may change when permanent codes are assigned. Used in hematology, pediatrics, and newborn screening for diagnosis of sickle cell disease and carrier identification.

When is CPT S3850 used?

Used in hematology, pediatrics, and newborn screening for diagnosis of sickle cell disease and carrier identification.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.