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S3854 Gene profile panel breast

S Codes

Also known as: breast cancer genetic panel, hereditary breast cancer testing

Comprehensive multi-gene panel testing for germline mutations associated with hereditary breast and ovarian cancer including BRCA1, BRCA2, and other predisposition genes.

In Plain Language

genetic test for breast cancer risk; cancer risk gene panel

Clinical Context

Used in medical oncology, surgical oncology, and genetic counseling for assessment of hereditary cancer risk in breast cancer patients and families.

RVU Information

CPT S3854 does not have a physician work RVU assigned by CMS. This is typical for supply, drug, and equipment codes — reimbursement is based on Average Sales Price (ASP), fee schedules, or payer contracts rather than the RVU system.

Billing & Documentation

S-codes are used by private payers (not Medicare) for services without a standard CPT or HCPCS code. Coverage varies significantly between insurers. Verify payer acceptance before billing and document medical necessity thoroughly.

Specialties

OncologyGenetic MedicineObstetrics/Gynecology

Frequently Asked Questions

What is CPT code S3854?

CPT S3854 (Gene profile panel breast) is a S Codes code. Comprehensive multi-gene panel testing for germline mutations associated with hereditary breast and ovarian cancer including BRCA1, BRCA2, and other predisposition genes.

Is S3854 covered by insurance?

S3854 is a temporary HCPCS code. Coverage varies by payer and may change when permanent codes are assigned. Used in medical oncology, surgical oncology, and genetic counseling for assessment of hereditary cancer risk in breast cancer patients and families.

When is CPT S3854 used?

Used in medical oncology, surgical oncology, and genetic counseling for assessment of hereditary cancer risk in breast cancer patients and families.

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CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.