Home
Career Stage
Medical Students Residents Attendings CPT Codes Resources Blog Support

38226 Car-t prep t lymphcyt f/trns

Surgery

Also known as: CAR-T manufacturing, T-cell modification

Preparation and genetic modification of T lymphocytes for chimeric antigen receptor T-cell therapy including transduction and expansion.

In Plain Language

Engineering immune cells for cancer

Clinical Context

Manufacturing phase of CAR-T therapy involving transduction of T cells with CAR construct and ex vivo expansion.

RVU Breakdown

Work RVU0.77
Total RVU0.77

Est. Medicare Payment

$25.72

National estimate based on 2026 CMS PFS Conversion Factor ($33.40). Actual payment varies by locality (GPCI adjustment).

Billing & Documentation

As a surgical CPT code, proper documentation must include the operative report detailing the procedure performed, patient positioning, approach, findings, and any complications. Ensure the diagnosis code (ICD-10) supports medical necessity for the procedure.

How This Code Compares

With a work RVU of 0.77, this code ranks in the 3rd percentile among Surgery codes — 10.4x below the median (8.00). The highest wRVU in this category is 106.19.

Specialties

Hematology/OncologyImmunotherapyCell Therapy

Frequently Asked Questions

What is CPT code 38226?

CPT 38226 (Car-t prep t lymphcyt f/trns) is a Surgery code. Preparation and genetic modification of T lymphocytes for chimeric antigen receptor T-cell therapy including transduction and expansion.

What is the wRVU value for CPT 38226?

The work RVU for CPT 38226 is 0.77. This code is primarily used by Hematology/Oncology, Immunotherapy, Cell Therapy.

When is CPT 38226 used?

Manufacturing phase of CAR-T therapy involving transduction of T cells with CAR construct and ex vivo expansion.

Track This Code in RVU Edge

Log procedures, calculate wRVUs, and benchmark against MGMA data — all in one app.

CPT® is a registered trademark of the American Medical Association. Data sourced from CMS Physician Fee Schedule RVU26A. Descriptions, synonyms, and clinical context are original content by RVU Edge.